Tag Archives: World TB Day

Birkbeck natural sciences researchers continue to drive the fight against drug-resistant tuberculosis 

This World TB Day (24 March), Professor Sanjib Bhakta from Birkbeck’s School of Natural Sciences reflects on the ongoing global challenge of tuberculosis and how Birkbeck researchers are contributing to the fight against drug-resistant infections. 

On 24 March each year, World TB Day serves as a powerful reminder that tuberculosis (TB), a disease many consider a relic of the past, remains one of the deadliest infectious diseases worldwide. Caused by Mycobacterium tuberculosis, TB continues to claim nearly 1.5 million lives annually, disproportionately affecting communities in low- and middle-income groups locally in London and globally. 

The story of TB research began in 1882, when Dr Robert Koch announced his discovery of the TB bacillus, transforming scientific understanding of the disease. More than a century later, the challenge has evolved. Today, the rise of antimicrobial resistance (AMR) and the burden of prolonged, complex treatment regimens demand new and innovative solutions. 

At Birkbeck, University of London, the Mycobacteria Research Laboratory is at the forefront of this global effort. Through cutting-edge research in molecular microbiology and biochemistry, the team is working to develop new therapeutic strategies to combat drug-resistant mycobacterial infections. 

A key milestone in this journey is a new collaboration with the Ineos Oxford Institute, as part of the Oxford Consortium on Drugs for Drug-resistant TB (OxCoD4TB). This partnership brings together leading researchers, clinicians, and industry experts to accelerate the discovery of next-generation TB treatments. This spirit of collaboration and innovation was on full display at the Ineos Oxford Institute’s annual Early Career Researcher Conference 2026 this month, hosted at Saïd Business School, University of Oxford. Bringing together more than 200 participants from across disciplines, including microbiology, drug discovery, genomics, clinical science, and social science, the conference provided a vibrant platform for sharing ideas and forging new partnerships. 

Birkbeck’s School of Natural Sciences team of early career researchers made a strong impact at the event. Among them, Dr Nupur Angrish, a postdoctoral scientist, was awarded the Best Poster Prize. Reflecting on the experience, she described the conference as “incredibly inspiring,” highlighting the breadth of approaches being taken to tackle AMR. She added: “It means a great deal to have our work recognised by such an engaged and knowledgeable audience.” 

Dr Ankita Nag (left) and Dr Nupur Angrish (right) presenting their research posters at the IOI Oxford Early Career Researchers Conference 2026. 

Beyond the conference, Birkbeck’s contribution to World TB Day also extends to global policy and public engagement. This week, I am co-chairing a session at the UCL–LSHTM World TB Day event at Great Ormond Street Hospital, exploring how artificial intelligence could help accelerate progress towards ending TB – an area of growing importance in infectious disease research. 

Tackling TB, particularly drug-resistant forms of the disease, requires coordinated, global action. We must use antimicrobials responsibly while strengthening effective prevention, quicker detection and shortening, and simplifying TB treatment to deliver a faster, more efficient cure. 

Echoing the World Health Organization’s World TB Day call, “Yes! We can End TB!”, progress will depend on country-led action, people-powered change, and a united One Health effort. 

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Tackling drug-resistant TB: my cross-border mission as a Birkbeck Commonwealth Scholar

Gourav Rakshi is a Commonwealth Split-Site PhD Scholar based at Birkbeck, University of London. He’s recently actively shared his research to mark World TB Day, World Health Day, presenting his investigative work to a broader community of scientists and early career researchers.

I’m a Commonwealth Split-Site PhD scholar conducting research at the ISMB-Mycobacterial Research Laboratory within the School of Natural Sciences at Birkbeck, University of London. I’m also a member of the UCL-TB Centre. My research is jointly supervised by Professor Venkatesan Jayaprakash (Birla Institute of Technology, Mesra, India) and Professor Sanjib Bhakta (Birkbeck, University of London, UK), and my interdisciplinary project contributes to a UK-India education and research initiative aimed at accelerating the development of novel therapeutic interventions against drug-resistant tuberculosis (TB).

On 21 March, I presented a poster at the IOI Early Career Researcher Conference 2025, held at Saïd Business School, University of Oxford. This conference fosters interdisciplinary collaboration among researchers, clinicians, industry experts, and postgraduate students, encouraging innovative, multidisciplinary approaches to tackling antimicrobial resistance (AMR).

A few days later, on 24 March, I delivered a Turbo Talk at the World TB Day Symposium 2025, held at the John Snow Lecture Theatre, London School of Hygiene & Tropical Medicine (LSHTM). I was honoured to receive first prize for my presentation. This annual symposium brings together the global TB research community – including scientists, clinicians, policymakers, and affected communities – to share insights on TB research, control strategies, diagnostics, and policy development, while addressing future challenges.

World TB Day, observed on 24 March each year, commemorates the day in 1882 when Dr Robert Koch announced his discovery of Mycobacterium tuberculosis as the causative agent of tuberculosis. The symposium, jointly hosted by the UCL-TB and LSHTM TB Centres, highlights current TB research, control measures, and policy initiatives, connecting a wide range of stakeholders – from researchers and healthcare professionals to diagnostics experts and members of affected communities.

UCL-TB/ LSHTM-TB World TB Day Symposium 2025

Continuing my engagement with the wider scientific community, I participated in a panel discussion on 2 and 3 April at the 4th ACE Drug Discovery Summit, held at Insurance Hall, London. The session, titled In Vitro and In Vivo Testing of Drugs to Accelerate New Drug Discovery: Complementary Approaches, featured leading experts from academia and industry. During the event, Professor Bhakta delivered a keynote lecture on Models and Methods in Antimicrobial Drug Development (for further reading: https://pubmed.ncbi.nlm.nih.gov/38949698/). Other distinguished panellists included Soroush Safaei, Senior Principal Scientist at Sanofi; Chandan Seth Nanda, Vice President of Target and Drug Discovery at Pear Bio; Annick Sawala, Head of Translational Research at Vivan Therapeutics; and Bilada Bilican, Senior Director at AstraZeneca’s Applied Stem Cell Sciences, Centre for Genomics Research. The ACE Drug Discovery Summit provided an excellent platform for global experts to explore trends, challenges, and innovations in drug discovery through presentations and interactive sessions.

Reflecting on these experiences, I can say that as a final-year PhD student, presenting my work to an international audience and engaging in meaningful discussions with both academic and industry leaders has been incredibly rewarding. This journey wouldn’t have been possible without the support of the Commonwealth Scholarship, and I’m deeply grateful to my doctoral training supervisors for their unwavering support and mentorship.

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